Monday, September 15, 2008

Hair gives little sun protection for scalp


Friday, 12 September 2008 Anna SallehABC

Sun visors may keep the sun off your face, but what about your scalp?

A full head of hair provides surprisingly low protection for your scalp from the sun, Australian researchers warn.

Physicist Associate Professor Alfio Parisi and colleagues, from the University of Southern Queensland in Toowoomba, report their findings in the journal Photochemistry and Photobiology.

The researchers say a significant number of melanomas occur on the scalp, with one study showing they make up 13% of melanomas. "So the question arose how UV penetrates through the hair," says Parisi. Parisi and colleagues studied how much ultraviolet (UV) radiation from the sun got through to the scalp with a full head of hair. They placed a UV sensor in the centre of the top of the head of a mannequin adorned with a wig made of human hair. The researchers then tested how much UV got through when the sun was at different positions in the sky.

"It started about 9 o'clock in the morning right through to lunch time," says Parisi.

He and colleagues also tested what happened when the head was upright or tilted towards the sun, and what happened under the shade of a beach umbrella. They also tested the impact of grey and brown hair, and short (4.9 centimetres) and long (10.9 centimetres) hair. Short hair may have an edge They found that the colour of the hair made no difference, but that short hair may provide marginally more protection than long hair. Parisi thinks this is because long hair weighs itself down at the part and exposes more of the scalp to sun.

Overall, the researchers found hair offered a protection factor ranging from 5 to 17, which is significantly lower that the average sunscreen, which offers a protection factor of 30.

"This is much lower than properly applied sunscreen," says Parisi. "I'm surprised that the protection factor is so low."

While previous studies have measured hair's ability to protect the top of the ears, Parisi says this is the first study to measure its ability to protect the scalp.
"People who are going to be outside for a long period of time - even if they've got a full head of hair - should really wear a hat," says Parisi, warning that sun visors, and even caps, allow parts of the head to be exposed to the sun.

The Australian Bureau of Statistics reports that an estimated 1.2 million Australians work outdoors and there are more than 300 occupations that require mainly outdoor work.

A previous study found that outdoor workers are exposed to 5 to 10 times more UV radiation than other workers. "Males are twice as likely to die from melanoma, in all likelihood because of the higher rate of men in outdoor jobs," say Parisi and colleagues.

Thursday, September 11, 2008

Skin mapping


Skin mapping — or mole mapping — takes a lot of the guesswork out of skin-cancer worries

By Sarah Lemon

Former California “beach baby” Linda Savercool had her first brush with skin cancer at age 21.

The red spot on her chest was the common but rarely serious basal cell carcinoma. But removal of the pinhead-sized patch was just the first in a series of more than 50 atypical moles and cancerous or pre-cancerous lesions cut from Savercool’s skin by the time she was 40.
“When you’re 21 and young, you don’t listen,” she says.

Despite Savercool’s medical history and unusually large number of moles, not one of her physicians ordered a complete skin examination or “mole mapping” session before she became a patient of Medford dermatologist Dr. David Trask about four years ago. “He didn’t know where to begin,” Savercool says. “I have a lot of moles; they’re everywhere.”

Trask’s initial examination documented Savercool’s skin condition with digital photos and by plotting on paper the presence of lesions. The approach is intended to track changes in patients’ skin status and give dermatologists a way to verify their memories of particular moles.

“When a person has 100-some moles on their back, you can’t just look and go, ‘That’s new,’ ” Trask says. “The idea of taking photographs has taken root.”

The session didn’t stop there. Two or three of Savercool’s moles — deemed too suspicious to simply keep under surveillance — were removed then and there. Lab tests revealed characteristics of a pre-melanoma condition.

“If there’s even a chance a lesion is changing, we’re not going to sit on it,” Trask says.

Yet new moles seemed to pop up as quickly as others could be removed. Savercool’s subsequent dermatology appointments became a sad parody of “eenie, meenie, minie, moe.”

“It changes so fast,” Savercool says. “It can happen just overnight.”

For an entire year, Savercool, 52, endured the excision of five to eight moles every two weeks — nearly 100 moles in all. New surgery sessions practically coincided with removal of stitches from the prior visit, the Central Point resident recalls.

“It was pretty painful — my back was the worst,” she says.

“I have, you know, lots of scars,” she says, adding that the biggest on her arms and right leg are 2 to 3 inches long.

However, it’s the anticipation of biopsy results, Savercool says, that “kills” her, even since she started seeing Trask just once every three months.

“You’re waiting for the shoe to drop,” she says.

“I still don’t know what tomorrow could bring.”

While only 35 out of almost 100 moles have shown signs of basal cell carcinoma, pre-melanoma or other atypical features, Trask has assured Savercool, whose case is one of his most unusual, that a reprieve is unlikely.

“This is my life,” she says.

Savercool’s numerous scars have become a conversation starter at the Medford gym where she lifts weights three times per week. She’s aghast when friends tell her they’re going sunbathing or have an appointment at a tanning salon. Although Savercool’s olive-toned skin tanned easily, she still bubbled, blistered and peeled under a sheen of baby oil more times than she cares to remember.

“I just recommend people stay out of the sun — sunscreen or not,” Savercool says. “Nobody is safe. You don’t even have to have moles.”

Stacey Boals didn’t. But the 49-year-old Medford resident had developed an extremely rare and deadly form of skin cancer, noticed not a moment too soon.

Boals initially saw Trask for removal of a few “sun spots” that were later identified as basal cell carcinoma. A complete skin exam with photos wasn’t deemed necessary in her case.

Five years later, Boals was back in Trask’s office and offhandedly mentioned a raw patch on her thigh that she suspected was irritated when she shaved.

Biopsied, the spot proved a rare form of melanoma, completely lacking in pigment and requiring a surgeon’s expertise. A biopsy of Boals’ lymph nodes confirmed the cancer hadn’t spread. The 4-inch scar, which Boals has dubbed her “shark bite,” is a sobering caution against complacency.

“It was like a crater in my leg because they go deep,” Boals says. “I’d rather have that than the alternative.”

Boals’ and Savercool’s stories both illustrate Oregon’s status as a “hot spot” for skin cancer, Trask says. The trend, he and other dermatologists say, can be traced to a few factors: sun exposure through traditional occupations, such as logging, fishing and farming; an influx of former California residents who soaked up too much sun farther south; the state’s growing number of baby boomers, most of whom never wore sunscreen in their youth; and the state’s primarily Caucasian population, the group most affected by skin cancer.

“Skin cancer is pretty epidemic in this neck of the woods,” says Dr. Douglas Naversen, senior partner in Dermatology and Laser Associates of Medford.

“We get a lot of transplanted skin cancers in ex-beach boys and beach girls,” Naversen says.

“We have our hard-working farmers and ranchers ... The last thing they’re thinking about is putting on sunscreen.”

Whereas his practice 25 years ago treated approximately four cases of invasive melanoma per year, Dermatology and Laser Associates’ four physicians each see a case of melanoma about once every week, Naversen says. Although the cure rate for melanoma is 92 percent nationwide, an improvement over recent years, Naversen says, the total number of U.S. melanoma deaths continues to increase.

Statistically, Americans have a one in 70 chance of developing melanoma in their lifetimes, Trask says. In 1935, it was a one in 1,500 chance, he adds.

“Unfortunately, melanoma is one of the deadliest cancers known to mankind,” Trask says, adding that vaccines are experimental and chemotherapy often isn’t effective.

“Once it gets loose, it’s hard to stop it,” Trask says. “The earlier you catch it, the more likely you can be cured.”

Prevention, dermatologists say, is a matter of knowing the ABCs for melanoma and atypical moles: asymmetry, borders, color, diameter and evolution.

While instruments called dermatoscopes can be used to magnify moles and other lesions during an exam, Trask and Naversen primarily employ digital cameras capable of zooming in on a spot to take as many pictures as they believe necessary. Medical photography often is not covered by insurance.

Trask encourages everyone to self-examine their skin once a month, including the scalp. Anyone who’s had melanoma should see a dermatologist at least every six months, he adds. Diagnoses of other types of cancer, such as basal cell, should be followed by yearly visits to a dermatologist’s office.

Those who have never had a skin-cancer diagnosis should be aware that their risk for the disease increases if relatives like parents, siblings or grandparents have had skin cancer, Trask says. Instances of skin cancer pick up after age 20, he says, although his youngest melanoma patient was 11.

The presence of more than 50 moles on a person’s body also indicates an increased risk for skin cancer, he says, adding that the average number of moles is about 40. About 20 percent of melanoma arises from pre-existing moles, Trask says.
“The more moles you have, the more at risk you are.”

Trask dispels the notion that removing melanoma causes it to spread. In reality, melanoma spreads by penetrating deeper into the flesh, he says, requiring surgeons to err on the side of removing more tissue rather than less.

“The risk of not removing it could allow you to die,” Trask says.
Savercool has learned the shocking reality that the ratio of mole-to-scar sometimes doesn’t follow any logic. Excision of dime-sized, pre-melanoma lesions on her back healed to 1-inch scars while others the size of a pencil lead’s thicker end resulted in a 3-inch incision. The scars aren’t as frightening as the possibility that cancer could return to some of the same spots.

“Now I do not go in the sun,” Savercool says. “I wish I never would have done it.”



Frequently Asked Questions
Q: What does mole mapping mean?

A: Medical photographs are used by dermatologists to follow lesions over time. Often, patients have overview photos taken that can help detect new lesions. Mole mapping also includes close-up photography of atypical moles. Lesions are numbered on your body and a diagram, or “map,” is used so the photographed lesions can be compared on subsequent examinations. This allows your physician and you to follow individual lesions more closely to detect changes early.


Q: What happens during the visit?

A: First, a physician will see you in the dermatology clinic where you will have a full-body skin exam. Moles that appear unusual and would benefit from close-up photography would be identified and photos taken. A map is made of these moles to be used during subsequent exams.


Q: What should I wear?

A: Because you will be undressing, wear comfortable clothing and shoes that are easy to put on and take off. Remove jewelry and watches, and if you have long hair, bring something to pull it back into a ponytail. During the physician visit, you will be asked to completely undress and be given a gown. You will be draped appropriately during the exam. During the photography session, remove as much of your clothing as you are comfortable with, the more the better. If you are unable to undress completely, bring underwear that you will be comfortable wearing that covers the least amount of skin. Avoid “sports bras.”


Q: How long does this take?

A: Complete skin examinations could take 30 minutes to 2 hours, depending on a patient’s number of moles and the number of photos taken.


Q: Does insurance cover the visit?

A: Insurance will be billed for the physician portion of the visit similar to a routine doctor’s visit. The cost of medical photography is not routinely covered by insurance companies, although there may be exceptions. The cost depends on how many photographs are taken.


— Source: Oregon Health and Science University Department of Dermatology


ABCs of melanoma and atypical moles

Asymmetry — One half does not match the other in size, shape, color or thickness.

Border — A ragged, scalloped or poorly defined border that can fade imperceptibly into surrounding skin.

Colored — Pigmentation is not uniform. Shades of tan, brown, black are present. Dashes of red, white and blue add to the mottled appearance

Diameter — Melanomas are usually greater than 6 millimeters in diameter or approximately the size of a pencil eraser when diagnosed. They can, however, be smaller. Any mole this size or larger is considered atypical.

Evolution — If a mole is different from others, changes, itches or bleeds, see a dermatologist.

Tuesday, September 09, 2008

Sun lovers at risk for vitamin D deficiency, too

By JEFF WEBERSTAFF WRITER

Our society's passion for using sun block as protection from getting skin cancer is wise and advocated by most — if not all — health-care professionals, but slathering on too much sunscreen also can harm your body.

"The regular use of effective sunscreens decreases a person's ability to produce vitamin D," says John Bucek, director of the Somerset Family Medicine Residency program at Somerset Medical Center in Somerville.

Bucek and other experts suggest taking in at least 15 minutes of direct sun a day before applying sunscreen. But those at risk or with a history of skin cancer or with sun-sensitive skin conditions first should check with their doctor or dermatologist before employing this directive.

Dark-skinned people also are more at risk because they absorb ultraviolet light less quickly than fair-skinned people, according to Tanya Edwards, head of the integrative medicine department at the Cleveland Clinic.

Did you know?

According to Bucek, many experts believe that people who have vitamin D deficiency suffer from more inflammation and symptoms and take longer to return to normal when experiencing the common cold. That's because vitamin D is used by the immune system as a messenger to immune cells. The type and degree of inflammation can be regulated up or down by simply ingesting normal amounts of vitamin D.

Friday, April 11, 2008

Deadly Cancer Could be Related to Sun Exposure

Deadly Cancer Could be Related to Sun Exposure
April 10, 2008

The skin cancer melanoma is no longer the only killer skin cancer to be concerned about. Now, there is another cancer that may also be related to sun exposure. Patty Ruiz grew up in sunny Las Vegas and if there's any doubt that protecting your skin from the sun is a good idea, just ask her.

"I had 8 chemo treatments. I had my last one last Friday. So I'm all finished with chemo now," said Parry Ruiz, who is fighting melanoma. The dangerous form of skin cancer is generally caused by exposure to the sun and periodic sunburns. In her case, it was discovered in an advanced stage. "Boy, I wish I could turn back time and put that sunscreen on, she said. Las Vegas oncologist Paul Michael says melanoma can surface at any age and practically anywhere on the body.

"Many times it shows up where the sun never shines. It can be in our buttocks, on the bottom of our legs, feet," said Dr. Paul Michael, oncologist.

Now, an equally dangerous, though much less common form is skin cancer, merkel cell carcinoma, that nearly always occurs in people over 50, is showing up more often in Southern Nevada. It may appear as harmless bump.

"More elderly, retired people are living where they're exposed to the sun. And there is a theory that merkel cell tumor is a type of skin cancer that could be related to sun exposure. We just don't know for sure," said Dr. Michael.

There may also be a connection between merkel cell carcinoma and a deadly form of lung cancer -- as the two are very similar. Dr. Michael would like to see more research, especially in the area of treatment.

"How does chemotherapy help merkel cell? We know that it can help melanoma patients like Patty. But we don't know for sure if merkel cell responds well to chemotherapy. There's a lot of interest in that," he said.

A biopsy is the only way to know for sure what kind of skin cancer a person has and therefore, how to treat it. While merkel cell appears mostly in the elderly, melanoma is one of the most common cancers in young adults.

Wednesday, February 27, 2008

Gilbert more focused after melanoma scare

A cancer scare a year ago is fueling newfound ambitions for Belgian attacker Philippe Gilbert (Française des Jeux) heading into this year’s classics campaign.

At the beginning of the 2007 season, the 25-year-old was alarmed by the sudden appearance of any ugly black mole on his left leg and immediately went to the doctor. Before he knew it, he was hustled into surgery not knowing whether or not he’d ever race again.

“The doctor said I should have it removed and I lost 10 days after surgery waiting to hear the results,” Gilbert told VeloNews. “Thankfully, it wasn’t melanoma. That is the most dangerous cancer. It was very scary.”

Melanoma is one of the deadliest forms of cancer and there’s been a recent spike of several high-profile cases among the peloton. Cyclists can be especially susceptible to the cancer after spending hours a day training and racing under the glaring sun.

Magnus Bäckstedt (Slipstream-Chipotle) had a cancerous melanoma successfully removed from his chest in 2006. American racer Amber Neben had a tumor removed from her back following last year’s world championships in Stuttgart, Germany, and is also enjoying a full recovery.
Early detection is key and Gilbert is thankful he quickly followed up with a doctor’s visit when he discovered the suspicious growth.

“Cyclists must be more aware because we are all day under the sun,” Gilbert said. “With the pollution and the ozone, the sun is stronger and more dangerous. I am using more sun screen than before.”

Gilbert, one of the few top Belgian riders hailing from the French-speaking Wallonia region, admitted the cancer scare threw him off during his 2007 campaign.

Following success in a five-win 2006 campaign capped by victory in the season-long French Cup series, he only managed one victory in 2007 that didn’t come until August.

“It was very scary. I’m okay now and back to full health,” he said. “I have regular surveillance of my skin now.”

Gilbert says the brush with cancer is giving him extra inspiration coming into 2008 campaign. The fruits of that newfound motivation were on clear display at the Mallorca Challenge earlier this month.

Gilbert uncorked one of his classic late-stage attacks to surprise the sprinters in stage 1 and then won again in stage 3 despite sending José Rojas (Caisse d’Epargne) into the barriers. He won the unofficial overall prize after fending off attacks from Toni Colom (Astana) and Aitor Perez (Extremadura-Spiuk).

It was Gilbert’s first stage-race victory of his career marked by random stages and one-day classics.

“The success in Mallorca bodes well for my spring season. I will try to be at my best for the important races this season,” Gilbert said. “I dream of winning one of the big races, Milan-San Remo or Liège. Since I live only 30 kilometers from Liège, that is my dream since a child.”
Since turning pro in 2003, Gilbert has attracted a lot of attention in the Belgian media, especially in the French-speaking eastern half of Belgium. Most successful Belgian riders hail from Flanders in western Belgium.

This year, Gilbert is more ambitious than ever.

First, he will focus on the Ardennes classics before taking a break and reloading for the Tour de France. He’ll stay busy with slated appearances in the Summer Olympic Games, the Vuelta a España and the world championships.

His ability of uncork daring attacks in the decisive late stages of races will remain his favored tactic.

“My problem is that I can sprint well, but not fast enough to beat the likes of Bettini, Freire or Bennati,” he said. “So I must try my luck with some well-timed attacks. Last year at Milan-San Remo, we were only caught with just less than one kilometer to go. That’s what I have to do to try to win one of the big races. It doesn’t work very often, but when it does, it’s quite beautiful.”

Velonews.com

February 27, 2008

Tuesday, January 08, 2008

Multiple Skin Cancer Risk Behaviors

Multiple skin cancer risk behaviors are common among US adults

Whether you’re basking on the beach during vacation, coasting down glittering white snow on a weekend ski trip, or simply walking the dog or running errands, sunlight’s ultraviolet rays can damage your skin year-round. Yet a new study by behavioral researchers at Fox Chase Cancer Center shows that most American adults engage in multiple behaviors that boost their risk of skin cancer by increasing their exposure to UV rays.

These behaviors include infrequent use of sun-protective clothing; staying outside in the sun rather than seeking shade; infrequent use of sunscreen with a sun-protection factor (SPF) of 15 or more; indoor tanning with a sunlamp or tanning bed within the past year; and getting sunburned within the past year.

Collectively, skin cancer of all types is the most common cancer in the United States and the incidence has increased over the past three decades. During 2007, an estimated 1.1 million Americans received a diagnosis of basal- or squamous-cell skin cancer or the more invasive, potentially lethal melanoma, according to the American Cancer Society.

Heredity plays an important role in skin cancer. For example, a typical portrait of someone at risk of skin cancer would show a natural blonde or redhead with very fair skin that freckles and burns more easily than it tans. Melanoma, in particular, is known to run in certain families.
However, overexposure to ultraviolet light—something controlled by behavior—is a major factor in increased skin cancer risk, noted Fox Chase psychologist Elliot Coups, Ph.D., an assistant member in the psycho-oncology program at Fox Chase and lead author of the new study. The report appears Jan. 8 in the online edition of the American Journal of Preventive Medicine and in the February 2008 issue of the print edition.

The Fox Chase researchers found that younger adults were particularly likely to engage in multiple behaviors that increase skin cancer risk. Men, Caucasians, smokers, persons who consume high levels of alcohol and persons who report having skin that is not especially sensitive to the sun were also more likely to engage in behaviors that placed them at increased skin cancer risk.

“Descriptive information about the prevalence of multiple skin cancer risk behaviors and related factors such as age may inform the development of targeted protective strategies for specific high-risk groups,” Coups said.

“Since the UV damage to the skin is cumulative, lack of protection by young people is likely to drive a continued increase in skin cancers as these generations grow older over the next decades,” noted Stuart R. Lessin, M.D., director of dermatology at Fox Chase. “This new research on behavior relating to skin cancer risk may help us target the highest-risk groups with educational messages tailored for them.”

“Ultraviolet radiation exposure is the most important modifiable risk factor for all types of skin cancer,” Coups said. “Wearing protective clothing like a wide-brimmed hat, avoiding sun exposure during the middle of the day, when rays are strongest, seeking shade, using sunscreen and avoiding indoor tanning have all been recommended by various agencies, but all available data suggest that the majority of American adults don’t follow this advice and instead have high rates of UV exposure and sunburns.”

“A comprehensive approach to skin cancer prevention requires attention to multiple skin cancer risk behaviors that are common in the U.S. population,” Coups and his fellow authors concluded.
Although previous research had suggested that individuals had multiple risk-increasing behaviors, the current study is the first comprehensive analysis of the prevalence and correlates of multiple behavioral risks for skin cancer among U.S. adults. Correlates examined in this study include geographic location; demographic factors such as age, gender and education; health-care access; behavioral health risks such as smoking; family history of melanoma; perceived cancer risk; skin sensitivity to the sun; and having total skin exams.

Data for the study came from the 2005 National Health Interview Survey, an annual representative U.S. health survey in which 31,428 individuals participated. The researchers excluded individuals who had already had skin cancer or whose questionnaires contained missing data in key areas of the study, resulting in a study sample of 28,235 individuals.

Coups’ Fox Chase co-authors are Sharon L. Manne, Ph.D., director of the psycho-oncology program, and associate member Carolyn J. Heckman, Ph.D. A grant from the National Institutes of Health supported the research.

Fox Chase Cancer Center was founded in 1904 in Philadelphia as the nation’s first cancer hospital. In 1974, Fox Chase became one of the first institutions designated as a National Cancer Institute Comprehensive Cancer Center. Fox Chase conducts basic, clinical, population and translational research; programs of cancer prevention, detection and treatment; and community outreach. For more information about Fox Chase activities, visit the Center’s web site at www.fccc.edu or call 1-888-FOX CHASE.

Friday, November 09, 2007

Summer Is Over But Skin Cancer Is Not!

Summer Is Over But Skin Cancer Is Not!

06 Nov 2007 A new warning on skin safety was released by Crown Laboratories to draw attention to the fact that while summer is over, the high risk of skin cancer development is not.

"Many people still don't understand the difference between Ultraviolet-A rays (UVA) and Ultraviolet-B rays (UVB)," said Don Kilday, Doctor of Pharmacy and President of Crown Laboratories Inc., the manufacturer of the popular Blue Lizard Australian Sunscreen, located in Johnson City, Tennessee. Kilday added, "UVA is just as strong during the winter months as during the summer months. No matter what the temperature is outside, there is always a risk of sun damage on unprotected skin."

Even though you may not be expecting sun damage during the winter season, the UVA rays are still strong and deeply penetrate exposed skin. Although most U.S. sunscreens protect consumers from the UVB spectrum, it's the UVA rays that are most harmful because they penetrate deeper into the tissue causing damage. Kilday notes that a true broad-spectrum sunscreen containing at least 6% Zinc Oxide, with an SPF of 30 or higher should be used on areas of the body that are not concealed by clothing. This helps prevent wrinkles, skin spots and the biggest concern, skin cancer.

Oral medications, such as antibiotics, etc. plus many skin care products containing Alpha Hydroxy acids, Retin-A and other ingredients also heighten the risk of sunburn from UVA exposure.

"The skin is very vulnerable to sun exposure year round," says Kilday. "Education and making sun safety a daily regimen 365 days a year are the best defense against skin cancer." In addition, a recent study published on Springer Link, suggests that UVB rays are strongest in summer, but that the more harmful UVA rays show no noteworthy seasonal variation and are equally as strong in the winter months as they are in the summer months.

According to the American Cancer Society, skin cancer is the most common form of cancer and there will be one million new cases diagnosed in the United States this year. New cases of the deadly form of Melanoma will account for around 59,940 cases and of that number 10,850 will account in death. When detected in the early stages, Melanoma is almost always curable. Preventing and detecting the early stages of skin cancer through education, protection and proper sun safety tips will save lives.

Wednesday, November 07, 2007

Sun Hat - Editor's Choice Award

November 7, 2007

Dear Editors’ Choice Winner:

Congratulations! The editors of Organic Gardening magazine have selected The Adventurer Hat as a winner of our 2007 Editors’ Choice Award.

The Editors’ Choice Awards are presented to the best products used in our season-long evaluations. Our respected panel of test gardeners extensive experience and rigorous field-testing, combined with Organic Gardening’s 65 years of heritage as a trusted gardening resource make these awards the most highly credible mark of quality for the companies and products chosen.

As a winner of our Editors’ Choice Award, your product has been recognized for superior design, materials and performance. All winners withstood extensive field-testing by our editors and test gardeners. As a result, those selected for this year’s award are among an elite few who enjoy the privilege of bearing this mark.
Of course, the real winners here are our readers—and your customers. Through the devotion to quality by your team and the dedication of our staff, together we’re creating and sustaining gardeners and ensuring a more enjoyable gardening experience.

Congratulations again on being named a 2007 Editors’ Choice Award recipient by Organic Gardening magazine. We look forward to helping you make the most of this award.

Sincerely,
Scott Meyer - Executive Editor
Zazel Loven - Senior Editor

From the reviewer:

The Adventure Hat does much more than provide some shade, Pam says. The lightweight fabric fully blocks the sunlight, protecting your face, nose, ears, and back of the neck from harmful rays. "I love this hat," says the usually restrained Pam, and you can quote me."

groworganic.com

Tuesday, October 23, 2007

Broccoli Protects Against UV Radiation

Broccoli sprout-derived extract protects against ultraviolet radiation

A team of Johns Hopkins scientists reports in this week’s issue of the Proceedings of the National Academy of Sciences that humans can be protected against the damaging effects of ultraviolet (UV) radiation — the most abundant cancer-causing agent in our environment — by topical application of an extract of broccoli sprouts.
The results in human volunteers, backed by parallel evidence obtained in mice, show that the degree of skin redness (erythema) caused by UV rays, which is an accurate index of the inflammation and cell damage caused by UV radiation, is markedly reduced in extract-treated skin.

Importantly, notes investigator Paul Talalay, M.D., professor of pharmacology, this chemical extract is not a sunscreen. Unlike sunscreens, it does not absorb UV light and prevent its entry into the skin. Rather, the extract works inside cells by boosting the production of a network of protective enzymes that defend cells against many aspects of UV damage. Consequently, the effects are long-lasting; the protection lasts for several days, even after the extract is no longer present on or in the skin.

As skin cancer incidence is rising dramatically due to the escalating exposure of aging populations to the UV rays of the sun, Talalay says that “treatment with this broccoli sprout extract might be another protective measure that alleviates the skin damage caused by UV radiation and thereby decreases our long-term risk of developing cancer.”

The protective chemical agent in the broccoli sprout extracts is sulforaphane. It was first identified by Talalay and his colleagues more than 15 years ago and has been shown to prevent tumor development in a number of animals treated with cancer-causing chemicals.

After first testing mouse models of skin cancer to confirm sulforaphane’s protective effects, Talalay and his team tested six healthy volunteers. Each one was exposed to a pulse of UV radiation on small patches of their skin (less than 1 inch in diameter) that were either treated or untreated with different doses of broccoli extract.

At the highest doses, UV-induced redness and inflammation were reduced by an average of 37 percent. The extracts were protective even when applied three days prior to UV exposure. The protection did vary considerably among the subjects, ranging from 8 percent to 78 percent, which Talalay notes may be due to genetic differences among individuals, local differences in the skin, or other factors such as dietary habits. He also points out that conventional sunscreens were essentially ineffective in these experiments.

Source: Johns Hopkins Medical Institutions

Friday, October 05, 2007

The Miracle of Cell Repair

UVA researchers explain cell response to skin-damaging UV rays.

CHARLOTTESVILLE, Va., Oct. 1, 2007 -- It’s well known that overexposure to ultraviolet rays from the sun can cause major skin problems, ranging from skin cancer to sunburns and premature wrinkles. A tan, for example, is nature’s own UV protection and an unhealthy sign that your skin is damaged.
But what is not so well known is exactly how UV rays specifically interact with your DNA and the complex organelles and proteins found inside every cell of your body.

Researchers at the University of Virginia Health System have published a new study that helps scientists around the world expand the body of knowledge on how cells protect themselves (or not) from DNA damage caused by UV rays.

Their study reveals part of a “simple switch” mechanism inside cells, triggered by UV exposure from the sun, that helps our cells survive and thrive after being exposed. This mechanism involves an unanticipated connection between several proteins in the cell, the researchers discovered.

Their findings, published in the September 7th online issue of the journal Cell, describe part of a pathway inside human cells that regulates when and how cells repair damage to their DNA when irradiated with UV rays. The research was conducted by Ian Macara, PhD, professor of microbiology at UVa’s Center for Cell Signaling, along with two MD/PhD students at UVa, Brandon Kremer and Laura Adang.

“When cells get DNA damage, normally they stop moving and stop responding to stimuli until they are repaired,” Macara explains. “We detail in this paper how a certain protein, called SOCS7, moves from the cytoplasm into the cell nucleus and essentially instructs the cell to stop dividing via a protein called NCK. The role of SOCS7 is both to stop outside signals from being relayed to the cell and to switch on the cell’s response to radiation damage. Cancer can arise if the repair work is not performed properly.”

The SOCS7 protein is known to be involved in the body’s insulin response to blood glucose levels, but Macara said he was surprised to find SOCS7 involved in the response to cellular DNA damage as well. Macara said it will now be important to study whether the absence of SOCS7 in cells would make a person more susceptible to skin cancer.
###

The paper was supported by grants from the National Institutes of Health. Titled “Septins Regulate Actin Organization and Cell Cycle Arrest Through SOCS7-Mediated Nuclear Accumulation of NCK”, this research can be found online at: http://tinyurl.com/38pe2d.

Wednesday, May 30, 2007

Got Sunscreen?

One 9-ounce bottle of sunscreen is enough for just one day in the sun for a family of four (if they reapply twice). So, for the single person, that means a 9-ounce bottle should last you just two sun-filled weekends.

Tuesday, May 29, 2007

Don't Panic!

Researchers predict by 2010, one in 50 Americans will develop melanoma at some point in their lives.

Doctors suggest a healthy balance of sun and shade, keeping tanning to a minimum by wearing a sun hat with more than a 3-inch brim, slipping on sun protective clothing at the shore and consistently applying recommended amounts of sunscreen. Also, remember to do your monthly skin check. Should you discover irregularities, prompt treatment is key -- seek a health professional's advice as soon as possible.

Tasty Beverage Can Protect Your Skin From Cancer

Most of us know the best way to protect yourself against skin cancer is to cover up with sun protective clothing and wear sunscreen, but you may be able to drink your way to safer skin as well.

"The use of sunscreens to cover up the best that you can from the sun, the use of sun hats and sun protective clothing during the day, and try to avoid the sun during the hours of 10 in the morning to two in the afternoon when the sun intensity is the greatest outdoors - that in combination with drinking tea -- I think would be useful," says dermatologist Dr. Bryan Chen.

Drinking just one cup of tea a day will lower your risk of getting the two most common types of skin cancer, squamos and basal cell carcinoma, according to the Journal of the American Academy of Dermatology."Teas have long been known to contain antioxidants in them -- and also chemicals called polyfenals," says Dr. Chen.In the first human study of more than 2,000 people tea's antioxidants were found to limit the effects of the sun's ultraviolet rays. But Doctor Chen says tea isn't the cure all for skin cancer." Just because you drink tea doesn't mean it's a 100% protection against the development of skin cancer -- you really do need to do it in combination with other protective measures protect yourself from the sun.

"Scientists found the more tea you drink, each day and over the years, the better the skin protection. It doesn't matter if the tea is hot or cold, and all types of tea offered sun protection, including green, black and herbal tea.

NBC - Web Editor: Online Content Producer, Matt Bush

Tuesday, March 13, 2007

Skin Cancer Campaign Targets Vanity

By Jessica Marszalek13mar07

YOUNG women who ignore health warnings about skin cancer may be coaxed out of the sun by a new campaign appealing to their vanity.

Visiting academic Dr Kristina Jackson today presented US research into reshaping attitudes on sun protection and discouraging sun tanning at a Brisbane medical conference hosted by the Queensland Cancer Fund and Queensland University of Technology.

Dr Jackson discussed her intervention method in which a group of young women were shown a video that promoted the beauty of pale skin, and the effects of skin cancer.

A follow-up four months later showed the women had reduced the time they spent sunbathing and took more precautions.

Queensland Cancer Fund SunSmart coordinator Lisa Naumann said Dr Jackson's research, which focused on the beauty benefits of avoiding the sun, would be looked at to see how it could be used to target young women in Australia.

She said young women often missed messages which drove home the possibility of developing skin cancer and it was hoped a different slant, showing the negative effects of sun exposure such as wrinkles, would be more effective.

She said measures such as photo-ageing had been used to drive home the message.

"(It was) not so much scare tactics but just saying this is the reality of it," Ms Naumann said.
"Just by showing them the damaging effects of the sun, it had a positive influence."

She said an advertising campaign could be used to encourage young women to "enjoy the skin they're in".

Thursday, March 08, 2007

Cancer-Fighting Gene Guards Against Sun Damage

Cancer-Fighting Gene Guards Against Sun Damage

THURSDAY, March 8 (HealthDay News) -- A gene that is known to play a key role in suppressing cancer also seems to protect against sun damage while promoting a golden tan.
The revelation could one day lead to better ways to prevent skin cancer, which roughly 1 million Americans develop each year.

"This finding provides us an opportunity to look at human populations with a varied risk of developing skin cancer and start to identify precisely what is regulating the risk of developing skin cancer rather than estimating," said senior study author Dr. David Fisher, director of the melanoma program at the Dana-Farber Cancer Institute at Harvard Medical School. "Right now, we're incredibly inaccurate in identifying risk and, therefore, in ameliorating risk."
The findings are published in the March 9 issue of Cell.

People who tan easily or have darker skin are much less likely to develop melanoma, the deadliest form of skin cancer.

"The tanning response is a protective response to injury, which can prevent further injury," explained Dr. Robin Ashinoff, medical director of Dermatologic, Mohs and Laser Surgery at Hackensack University Medical Center, in New Jersey. "On the one hand, the skin is the most common organ to be affected by cancer and, in principle, it ought to be preventable because we know the carcinogen which causes it, the sun."Still, rates of skin cancer remain high.

"That's a terrible state of affairs in 2007," Fisher said. "We really want to understand the impact of ultraviolet radiation on the skin and what is the molecular cascade that is occurring downstream."

Six months ago, Fisher and his team published a paper documenting the fact that keratinocytes -- cells closer to the surface of the skin -- react to sun exposure. Previously, it had been thought that pigment-producing melanocytes played this role.

Once keratinocytes are exposed to rays from the sun, they produce melanocyte-stimulating hormone (MSH), a growth factor which binds to the pigment cells (melanocytes) and stimulates them to produce pigment.

Differences in the MSH receptor explain differences in ability to tan. Redheads, for example, have a variant which doesn't respond at all to MSH, explaining why the Nicole Kidmans of this world don't turn a tawny bronze.

Fisher and his colleagues still didn't know, however, what happened within keratinocytes to stimulate MSH production.

"We knew that ultraviolet radiation causes MSH to be induced," Fisher said. "How is the ultraviolet radiation doing that? What is perceiving the radiation and translating that signaling into making more MSH?"

The key happens to be the tumor-suppressor gene known as p53, which is induced in almost every keratinocyte of human skin samples within an hour of being exposed to the sun's ultraviolet rays. "That activity is completely regulated by this protein," Fisher said.
The finding is biologically plausible, experts said.

"It makes sense that most skin cancers and cancers, for that matter, have mutations in the p53 because it functions to protect us. It basically causes abnormal cells to be killed or die, and regulates all sorts of pathways that protect us," Ashinoff said. "It's not surprising that something that would protect us would also stimulate mechanisms in the skin known for protecting us."
"Knowing this, we can now identify exactly where we would like to interfere with the risk," Fisher added. "Knowing that p53 is part of this process allows us to potentially identify drugs that might be able to restore this response at different steps, depending on where the person might need it, where their block is."

By Amanda GardnerHealthDay ReporterThursday, March 8, 2007; 12:00 AM

Friday, March 02, 2007

Maggy!


Its been a testing year for Magnus Backstedt the Liquigas rider who crashed on the opening day of his season in 2006 and suffered a career threatening knee injury, but Backstedt has now revealed a more sinister problem that he has also had to deal with alongside everything else. "I visited the doctor in December because of a mole that I didn't like the look of. He removed it anyway and said it was probably nothing to worry about.

Then in January I received the news that it was a malignant melanoma, skin cancer! I then had to have another operation where they took a piece of skin 9cm by 5 cm from my chest. As you can imagine I am now quite a beauty with my shirt off" He joked " We as bike riders whether you are a pro or otherwise, spend a lot of time in the sun. I have got the all clear, but I am now going to look at raising awareness of the risks of skin cancer. I am though ready to get back and put all this behind me. I am so fired up to get back to my best" He concluded.

Tuesday, December 19, 2006

Saving our Skins

"Healthy tan is an oxymoron," a dermatologist once said. The skin is telling you it's being damaged by ultraviolet rays. That damage related to mutations in the DNA is what is thought to lead to skin cancer. Nothing exists to reverse the DNA mutations that lead to skin cancer.

Every time you step outside or get into your car, your skin is exposed to the sun's ultraviolet rays. Over time , these UVA or UVB rays significantly increase the risk of cancer and hasten the signs of aging skin, such as wrinkling, sagging and discoloration.

Even people who avoid sun bathing or cover up at the beach don't think about wearing sunscreen or protective clothing every day.

What you're wearing makes a difference, too. Tightly woven fabrics offer the best resistance. A light T-shirt, on the other hand, offers little protection, about the equivalent of a sunscreen with a protection factor of SPF 5.

Curing skin cancer has a lot to do with how early you catch it. Prevention is always the best course!

Tuesday, November 21, 2006

Sun Hats & Sun Protective Clothing UPF Ratings

Fully effective sun hats and sun protective clothing should meet the highest industry and governmental standards. All fabrics used in the manufacture of sun hats and sun protection clothing should be independently tested and rated to guarantee compliance with the internationally accepted guidelines outlined in AS/NZS 4399:1996. In addition, sun hats and sun protective clothing should be designed to cover the maximum area of the body specific to their use, while allowing for comfort, fashion and ease of care. Note that no fabric, or garment gives total protection from the sun (refer to UPF Classification System below), because effects of the sun’s rays are cumulative over time, an individual could be subject to serious occurrences to the skin based on length and intensity of exposure.

The Ultraviolet Protection Factor (UPF) indicates how well a fabric/product protects the skin from solar UV and lets you select high quality skin protective clothing and sun hats with confidence.

UPF Classification System

UPF Ratings 15, 20 Good Protection, blocks 93.3% to 95.8% of sun UV rays
UPF Ratings 25, 30, 35 Very Good Protection, blocks 95.9% to 97.4% of sun UV rays
UPF Ratings 40, 45, 50, 50+ Excellent Protection, blocks of sun UV rays >97.5%



Tuesday, November 07, 2006

The sun is essential for life.

The sun IS essential for life. Yet, sunlight can also be a source of such deleterious effects as sunburn, and suntanning, as well as premalignant and malignant lesions. These may all occur in individuals with normal responses to sunlight. In addition, there exist a variety of "abnormal" photosensitivity responses to sunlight that may result from either endogenous imbalances (e.g. the porphyrias) or from added exogenous factors (e.g. drug photosensitivity). The "normal" responses to sunlight, by and large, are produced preferentially by UVB (290-320 nm), with minor contribution by UVA (320-400 nm) wavelengths. In contrast, the "abnormal" photosensitivity responses are, for the most part, elicited predominantly by long UVA and, in some cases, visible light.

Wednesday, October 18, 2006

Melanoma awareness saves lives.

If you're not in the sun a lot, why should you worry about melanoma?

Actually, melanoma (black mole cancer) is most common in people who work indoors and burn because of sun exposure on weekends and vacations. Your risk is greatest if you have light skin, eyes, and hair, or if you have a history of irregularly shaped moles. Melanoma is most common in people under 57, and it's the number one cancer in women 25 to 29. According to dermatologist Robert Friedman, M.D., a clinical associate professor at NYU Medical School, "Recent research indicates there may be a link between melanoma and pancreatic and breast cancer; a personal or family history of any makes you a candidate for another."

I didn't think a cancerous spot was such a big deal. Can't it just be removed?

"If you catch it early and excise it, melanoma is 100 percent curable," says Stephen Krant, M.D., the plastic surgeon who founded the SK Clinic in La Jolla, California. The death rate is going down, but the incidence of melanoma is rising. Dr. Krant advocates training aestheticians to point out questionable moles and suggest clients see their dermatologists. "Barbers, too, can be astute in spotting a lesion on the scalp," Dr. Friedman notes.

What's your best advice to prevent melanoma?

Boycott tanning beds. Wear cover-ups and wide-brimmed hats - see sundayafternoons.com for great styles. Apply sunscreen with an SPF of at least 15 and reapply frequently. Do self-exams (see sidebar) and get an annual head-to-toe check from your dermatologist (more often if you're at high risk). Also, says Anna Pavlick, M.D., an oncologist in New York City, "Have annual eye exams and wear sunglasses; the depletion of the ozone layer has caused an increase in ocular melanoma."

Performing a Self-Examination
  • Note the location and usual appearance of birthmarks, moles, and blemishes so you'll spot future changes.
  • Check the front and back of your body, then raise your arms and examine the sides.
    Examine your arms and hands.
  • Check the backs and fronts of your legs.
  • Look between your buttocks and around your genitals.
  • Sit and examine your feet, including the soles and spaces between toes.
    Check your face, neck, and scalp.
What to Look For

Robert Friedman, M.D., and his colleagues Darell Reigel, M.D., and Alfred Kopf, M.D., devised the ABCDE system. See a dermatologist if you find any of these warning signs.

  • Asymmetry: If the mole were folded in half, the sides wouldn't match.
  • Border Irregularity: The mole's edges are ragged, notched, or blurred.
  • Color: The mole is a non-uniform mixture of brown, black, red, white, or blue.
  • Diameter: The mole is wider than 6 millimeters (the size of a pencil eraser).
  • Evolving: The mole changes in size, shape, color, or symmetry.
From Susie Ellis